Differential cellular immune response of Galleria mellonella to Actinobacillus pleuropneumoniae
نویسندگان
چکیده
منابع مشابه
Galleria mellonella is an effective model to study Actinobacillus pleuropneumoniae infection.
Actinobacillus pleuropneumoniae is responsible for swine pleuropneumonia, a respiratory disease that causes significant global economic loss. Its virulence depends on many factors, such as capsular polysaccharides, RTX toxins and iron-acquisition systems. Analysis of virulence may require easy-to-use models that approximate mammalian infection and avoid ethical issues. Here, we investigate the ...
متن کاملNew to Galleria mellonella
EditoriAL Pathogens and their respective hosts interact closely leading to the host–pathogen framework response that could result in different outcomes that range from pathogen elimination to death of the host. To improve our ability to propose new measures that promote pathogen elimination and prevent host death, we need to have a comprehensive understanding of this interaction. Generally , mo...
متن کاملThe involvement of protein kinase A in the immune response of Galleria mellonella larvae to bacteria.
The role of protein kinase A (PKA) in the humoral immune response of the greater wax moth Galleria mellonella larvae to live gram-positive bacteria Micrococcus lysodeikticus and gram-negative bacteria Escherichia coli was investigated. The immune challenge of larvae with both kinds of bacteria caused an increase in fat body PKA activity depending on the injected bacteria. Gram-positive M. lysod...
متن کاملPhysical stress primes the immune response of Galleria mellonella larvae to infection by Candida albicans.
Larvae of the greater wax moth (Galleria mellonella) that had been subjected to physical stress by shaking in cupped hands for 2 min showed reduced susceptibility to infection by Candida albicans when infected 24 h after the stress event. Physically stressed larvae demonstrated an increase in haemocyte density and elevated mRNA levels of galiomicin and an inducible metalloproteinase inhibitor (...
متن کاملOP 4 . 1 The involvement of protein kinase A in humoral immune response of Galleria mellonella
The major challenges which plants have to withstand is osmotic stress (caused by drought, high and low temperature and high salinity), and wounding (caused by mechanical damage, f. ex. wind or herbivorous). Plant cells respond to these abiotic stresses by a multi-component defense strategy. Several families of protein kinases are involved in plant stress signaling. Among them are members of mit...
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ژورنال
عنوان ژورنال: Cell and Tissue Research
سال: 2017
ISSN: 0302-766X,1432-0878
DOI: 10.1007/s00441-017-2653-5